If the portal is using a HTTPS binding, and you need to update that certificate, you also need to update the PlatformCache service since it sets the certificate in the binding in IIS.
If PlatformCache is not updated, it will automatically wipe the link to the certificate in the binding.
- Update the certificate in windows, in the computer cert. store.
- Copy the thumbprint of the newly installed certificate.
- Open the file Ciresonportal\Platform\Platform_cache.config and paste the thumbprint at: SslCertificateThumbprint
- Restart the Platformcache service.